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Harlow, B

While this extreme outcome is rare with GLP-1 medications, subclinical thiamine insufficiency causing fatigue, irritability, and poor concentration is much more common
Adequate hydration, fiber supplementation, and stool softeners are common management strategies

Your options at that point are (1) switch to brand-name, (2) switch to a different GLP-1 agonist, (3) wait for generic availability, or (4) discontinue treatment
