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It is important to distinguish between evidence-based B12 replacement therapywhich is well-established for treating documented deficiencyand the use of lipotropic combinations, which lack robust clinical validation
[DOI] [PubMed] [Google Scholar] 296.Raaschou-Nielsen O
While these might seem like a bargain, they often provide poor value because so little of the active ingredient makes it past the gut barrier
Neurology 271 (7), 37823793
Here are a few common examples
