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In the same study, the human colon carcinoma cell line HCT116 was revealed to be less sensitive to the bleomycin treatment, in line with the very low expression of CT2 and with the metabolism based on glycolysis rather than on FAO (Table 1)

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It is thus difficult to be detected in body fluids compared to pCRP, which is supposed to show weak proinflammatory activities, and therefore, it is easy to be detected in blood [63]

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The binding of CRP to cellular FcRs that occurs in five C1q/FcR binding sites on the other face of CRP is supposed to account for its opsonizing properties, resulting in a response from phagocytic cells [156]