glutathione and iron toxicity Changes in ferrous promote ferroptosis and frailty in aging Caenorhabditis elegans Methylmercury induced ferroptosis by interference

Mechanism of regulation of intestinal epithelial tight junction proteins A crucial function of IECs is the maintenance of barrier integrity, which allows the permeability of essential ions, nutrients, and water but restricts the entry of bacterial toxins and pathogens 21

Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins

Although not evaluated here, lower intracellular GSH levels would also deactivate the GSH-dependent GPX4, further enhancing ferroptotic cell death (8, 38)

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