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Among non-diabetic patients without chronic kidney disease (CKD), there was a minimal increase of 0.01 mg/dL to 0.02 mg/dL in serum creatinine in the months following initiation of semaglutide, liraglutide, or tirzepatide

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Changes in the expression of GLP-1R, Iba-1, PI3K and p-Akt in the TNC were examined by western blotting