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Our findings demonstrate that M-SYFSY effectively reverses pathological metabolic reprogramming by inhibiting HIF-1-mediated transcriptional activation of key glycolytic enzymes including HK2, PDK1, and LDH

In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch

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doi: 10.1002/aur.2740 133 FungLKFloresREGuMSunKLJamesDSchuckRKet al

[Google Scholar] 30.N-acetylcysteine as an adjuvant to letrozole for induction of ovulation in infertile patients with polycystic ovary syndrome