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They differ on FDA-approval status, formulation, pharmacology, regulatory pathway, evidence base, and pricing each of which shapes the clinical and practical decision
At the cellular level, GLP-1 receptor activation appears to reduce the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)
Elevated insulin inhibits hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides
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