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Mechanism Comparison Source: FDA Prescribing Information Weight Loss Results Head-to-Head Trial The SURMOUNT-5 trial published in the New England Journal of Medicine represents the first direct comparison between these new weight loss drugs

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Each additional receptor target introduces new metabolic pathways into the compound's mechanism of action

Weeks 13 Through 16: Moving to 10 mg After at least four weeks at 7.5 mg, youll increase to 10 mg

Lastly, a post-hoc analysis of the aforementioned 26-week trial analyzed biomarkers to assessed insulin sensitivity and beta-cell function