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Postmarketing surveillance systems are also relatively slow, relying on formal reporting channels that may lag behind realworld experience
The 2013 AHA/ACC/TOS guidelines for the management of overweight and obesity in adults recommend bariatric surgery for patients with BMI 40 kg/m2 or BMI 35 kg/m2 with obesity-related comorbid conditions who are motivated to lose weight and who have not responded to behavioral treatment with or without pharmacotherapy

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Both medications were originally designed to treat diabetes

Mounjaro has a different drug class with a partially different side effect profile