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In a four-week clinical trial of 1,307 adults, participants that consumed 3.5 g/day of RPS experienced significantly greater abundance of Bifidobacterium and Akkermansia muciniphila as well as improved regularity and consistency of bowel movements compared to the placebo group
It is easily performed with reliable results and no radiation exposure, meaning it is safe for children and pregnant or breastfeeding people, but results may be affected by physical activity, malabsorption, and advanced lung, liver, or cardiac disease [62]
During this process they discovered that crude secretin separated into two fractions
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