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In this attempt, observational and experimental studies and review articles will be gathered from leading scientists in the field of diabetes mellitus.Areas to be covered in this Research Topic may include, but are not limited to:- Studies on the effect of SGLT2 inhibitors or GLP-1 receptor agonists on testosterone and gonadotropins in male patients with diabetes mellitus and hypogonadism- Studies on the effect of SGLT2 inhibitors or GLP-1 receptor agonists on testosterone gonadotropins in female patients with diabetes mellitus and p...

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Conclusions Combination of SGLT2i and GLP-1RA achieved significantly better cardiometabolic outcomes compared with SGLT2i alone

It is ideal for individuals who have completed the Metabolic Activation Protocol or who want daily support for metabolic consistency without aggressive intervention