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In contrast, the FREEDOM trial reported that the constant infusion of exenatide (20 ug daily for 3 months followed by 60 g daily) through an osmotic minipump was non-inferior to the placebo in 4156 T2DM patients (with a median follow-up of 16 months) (Ruff et al

Shared decision-making : If considering offlabel or prevention use, open discussion of uncertain benefit, possible side effects, cost, monitoring is essential

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