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This can lead to unwanted side effects of higher estrogen in men, such as fluid retention, breast tissue enlargement (gynecomastia), and decreased testicular size

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Beyond their hypoglycemic and metabolic effects, GLP-1based therapies have demonstrated anti-inflammatory effects, with in vitro and in vivo accumulating evidence demonstrating that GLP-1 reduces levels of inflammatory markers [[30], [31], [32]]

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