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23 In addition, these peptides may indirectly regulate AMPK activity to promote mitochondrial efficiency and FoxO transcription factors (Table 2)

Consequently, the challenge lies in knowing how to use the information provided in the table to estimate pKa values for compounds not explicitly listed

All these observations were confirmed and supported by in vitro experimental data, including evaluation of cytotoxic effects on healthy RBCs [269,270,271]
