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The first step in methionine catabolism is the generation of S-adenosylmethionine (SAMe), the principal biological methyl donor, in a reaction catalyzed by methionine adenosyltransferase (MAT) [55]

Author contributions Jonny J and Pasiak TF participated in conception and design

Expected Research Timeline: What the Data Shows Research protocols comparing these timelines often use the first 48 weeks to establish biomarker baselines before evaluating outcomes

[DOI] [PubMed] [Google Scholar] Dellinger RW, Holmes HE, Hu-Seliger T, Butt RW, Harrison SA, Mozaffarian D, et al