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B., Peisach J

Mol Pharmacol 72 : 769779

Dysbiosis and reduced blood flow disrupt gut microbiota, impairing digestion, nutrient absorption, and waste excretion

These findings strongly suggest that HG induces the onset of SCs pyroptosis and that pyroptotic SCs inhibit neuronal function and promote an inflammatory response (111), thus inhibiting pyroptosis in SCs has implications for neurons